SubgrpID: Patient Subgroup Identification for Clinical Drug Development

Function Wrapper contains four algorithms for developing threshold-based multivariate (prognostic/predictive) biomarker signatures via bootstrapping and aggregating of thresholds from trees, Monte-Carlo variations of the Adaptive Indexing method and Patient Rule Induction Method. Variable selection is automatically built-in to these algorithms. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output.

Version: 0.11
Depends: R (≥ 2.1.0), AIM, survival, ggplot2, Matrix
Imports: rpart, stats, glmnet
Published: 2017-03-04
Author: Xin Huang, Yan Sun, Saptarshi Chatterjee and Paul Trow
Maintainer: Xin Huang <xhuang.stats at gmail.com>
License: GPL-3
NeedsCompilation: no
Citation: SubgrpID citation info
Materials: NEWS
CRAN checks: SubgrpID results

Downloads:

Reference manual: SubgrpID.pdf
Package source: SubgrpID_0.11.tar.gz
Windows binaries: r-devel: SubgrpID_0.11.zip, r-release: SubgrpID_0.11.zip, r-oldrel: SubgrpID_0.11.zip
OS X El Capitan binaries: r-release: SubgrpID_0.11.tgz
OS X Mavericks binaries: r-oldrel: SubgrpID_0.11.tgz
Old sources: SubgrpID archive

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